Neurobiological effects of sphingosine 1‐phosphate receptor modulation in the cuprizone model
نویسندگان
چکیده
منابع مشابه
Neurobiological effects of sphingosine 1-phosphate receptor modulation in the cuprizone model.
Fingolimod (FTY720) is a sphingosine 1-phosphate (S1P) receptor modulator that regulates lymphocyte trafficking and exerts pleiotropic actions on oligodendrocytes (OLGs) and other neural cells. The purpose of this study was to investigate the role of S1P receptors in a non-T-cell model of demyelination, the cuprizone (cupr) model in C57BL/6 mice. Treatment with FTY720 (1 mg/kg) led to attenuate...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2011
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fj.10-173203